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Tramadol is a centrally functioning analgesic with several mechanisms of action. It inhibits serotonergic and noradrenergic nociception, while its metabolite O-desmethyltramadol inhibits -opioid receptor activity. It is said to have one-tenth the analgesic efficacy of morphine. Tramadol is used to relieve mild to (moderately) extreme acute and chronic pain.  Buy 150Mg Tramadol Online   Tramadol

When first starting out, doctors advise patients to take no more than 100 mg of tramadol. When tolerances increase, this number will be increased. However, the drug seems to have a daily limit of 300 to 450 milligrams. Adults—Start with 100 milligrams (mg) once daily. As required, your doctor can raise your dosage. However, the